Have you ever been tickled by someone then tried to tickle yourself and it didn't work? That's because your brain anticipates impact of your skin so the skin tightens up. It's the same as stubbing your toe. The reason stubbing your toe hurts a lot more than kicking something just as hard is because your brain anticipates you about to kick something so your skin tightens up. When you get hurt unexpectedly, your skin hasn't tightened up yet so it hurts more.
So when you tickle yourself, your brain knows what's coming so the skin tightens. But if someone comes up and tickles you by surprise, your brain wasn't anticipating the impact so your skin hasn't tightened yet.
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